Invokana (canagliflozin) with the right food regimen and workout can assist keep and decrease your blood sugar tiers when you have kind 2 diabetes. It also can decrease the hazard of coronary heart assault, stroke, and new or worsening kidney troubles in a few humans with kind 2 diabetes.
What is Invokana (canagliflozin)? How Invokana (canagliflozin) works?
Invokana (canagliflozin) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works withinside the kidneys to save you the absorption of sugar lower back into your frame. It lowers blood sugar with the aid of using inflicting your frame to cast off extra sugar via urine excretion.
What is Invokana (canagliflozin) used for?
- Type 2 diabetes
- Reduce the hazard of primary cardiovascular events (like coronary heart assault and stroke) in humans with kind 2 diabetes and mounted coronary heart disorder
- Reduce the hazard of end-level kidney disorder, doubling of serum creatinine (lab fee that measures kidney fitness), coronary heart-associated dying, and hospitalization for coronary heart failure in humans with kind 2 diabetes and diabetic nephropathy with albuminuria (extreme kidney-associated complications)
Invokana (canagliflozin) dosage forms
Typical dosing for Invokana (canagliflozin)
The endorsed beginning dose is one hundred mg as soon as day by day earlier than breakfast.
Frequently requested questions on Invokana (canagliflozin)
When need to Invokana (canagliflozin) be taken?
Invokana (canagliflozin) is typically taken earlier than the primary meal of the day.
Is Invokana (canagliflozin) tough at the kidneys?
Invokana (canagliflozin) is surely desirable for kidney fitness and function. This manner it may assist lessen the hazard of end-level kidney disorder, worsening of kidney function, and diabetic kidney disorder in adults with kind 2 diabetes.
Why did Invokana (canagliflozin) reason amputations?
There are many elements that play a position in amputation. The cause for Invokana (canagliflozin)-associated amputation isn’t always but actually understood. However, a records of earlier amputations, smoking, or diabetic foot infections can also additionally boom the possibilities of amputations. It may be very essential to speak in your issuer in case you revel in any leg or foot ache even as taking this remedy.
Does Invokana (canagliflozin) reason weight reduction?
Yes, Invokana (canagliflozin) can also additionally reason brief weight reduction. However, a have a look at from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) has discovered that weight reduction takes place for handiest a quick duration of time. Your weight can also additionally go back to everyday afterwards and an boom in cravings can happen. You need to preserve to consume healthful and workout regularly.
Is Invokana (canagliflozin) higher than metformin?
Metformin is a first-desire remedy for sufferers who’re newly identified with kind 2 diabetes. Invokana (canagliflozin) can be utilized in aggregate with metformin if blood sugar tiers aren’t managed or it is able to be used by myself if the individual can not tolerate metformin. Talk in your issuer to discover the proper remedy for you.
Pros and cons of Invokana (canagliflozin)
- In medical trials, become proven to decrease A1C tiers with the aid of using 1%
- Can be taken as soon as a day
- Less possibly to reason weight benefit and coffee blood sugar in comparison to different diabetes medicinal drugs
- Available as an aggregate drug with metformin referred to as Invokamet
- Can decrease the hazard of coronary heart assault, stroke, new or worsening kidney troubles, and dying in a few humans
- You can also additionally revel in accelerated yeast infections and urinary tract infections with Invokana (canagliflozin).
- There’s an unprecedented however extreme hazard of leg and foot amputations with Invokana (canagliflozin). Talk in your issuer in case you expand new ache or infections for your feet.
- May reason accelerated urination
- Avoid in case you are a heavy drinker of alcohol
- Not to be had in a inexpensive standard version
- Not a terrific alternative for humans with intense kidney troubles or on dialysis
- This remedy does now no longer deal with kind 1 diabetes or diabetic ketoacidosis (accelerated ketones withinside the blood or urine).
Pharmacist hints for Invokana (canagliflozin)
- Take as soon as day by day earlier than the primary meal of the day.
- Practice desirable hygiene to save you yeast and urinary tract infections.
- Be certain to drink lots of fluids due to the fact this remedy can reason dehydration.
- Make certain to test your blood sugar in case you do not experience properly or dizzy; this may be a signal of low blood sugar.
- Invokana (canagliflozin) isn’t always endorsed all through the second one and 0.33 trimesters of pregnancy.
- You need to preserve to workout regularly, consume a healthful food regimen, and take your different diabetes medicinal drugs at the side of Invokana (canagliflozin).
What are the aspect consequences of Invokana (canagliflozin)?
With any remedy, there are dangers and benefits. Even if the drugs is working, you can revel in a few undesirable aspect consequences.
Contact your health practitioner straight away in case you revel in any of the following:
May boom the hazard of leg and foot amputations. Call your issuer proper away in case you revel in any new ache or infections for your leg or foot.
The following aspect consequences can also additionally get higher over the years as your frame receives used to the drugs. Let your health practitioner realize straight away in case you preserve to revel in those signs or in the event that they get worse over the years.
Common aspect consequences
- Yeast infections (11%)
- Urinary tract infections (UTIs) (6%)
- Increased urination (5%)
Other aspect consequences
- Male genital yeast/fungal infections (4%)
- Thirst (3%)
- Constipation (2%)
- Nausea (2%)
- Vaginal itching (2%)