Does Farxiga Help With Weight Loss

By | September 18, 2021

What Is Farxiga?

Farxiga is a brand-call prescription medication. It’s permitted for exclusive makes use of in adults with kind 2 diabetes or coronary heart failure.

In humans with kind 2 diabetes, it’s permitted to:

  • enhance blood sugar degrees while used together with stepped forward food regimen and exercise
  • lessen the hazard of hospitalization for coronary heart failure in humans with coronary heart ailment or hazard elements for coronary heart ailment

In humans with coronary heart failure without or with kind 2 diabetes, it’s permitted to:

  • lessen the hazard of both hospitalizations for coronary heart failure or cardiovascular demise* in humans with decreased ejection fraction (EF).

It’s crucial to notice that Farxiga isn’t permitted to deal with kind 1 diabetes. And the drug additionally shouldn’t be used to deal with a circumstance known as diabetic ketoacidosis (DKA). (DKA is a existence-threatening circumstance that’s associated with diabetes.)

  • Cardiovascular demise is demise that’s associated with a coronary heart or blood vessel problem.
  • With decreased EF, your coronary heart isn’t capable of pump out as plenty blood to the relaxation of your frame as usual.

Drug Details

Farxiga may be utilized by itself or together with different diabetes and coronary heart failure medicinal drugs.

Farxiga comes as a pill you are taking through mouth as soon as daily. It consists of the lively drug dapagliflozin. And it belongs to a category of medicinal drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors.

Effectiveness

In scientific research, Farxiga reduced fasting blood sugar* degrees in humans with kind 2 diabetes through as much as 28.8 milligrams in line with deciliter (mg/dL). And the drug diminished their hemoglobin A1c (A1C)† degree through as much as 0.9�ter 24 weeks of treatment.

About 44% to 51% of humans withinside the research who took Farxiga for twenty-four weeks reached their intention A1C of much less than 7%.

To study Farxiga’s effectiveness for its different permitted makes use of, see the “Farxiga makes use of” segment on below.

  • Fasting blood sugar is measured after you’ve fasted for a positive duration of time. The American Diabetes Association (ADA) recommends a fasting blood sugar degree of eighty mg/dL to a hundred thirty mg/dL for maximum adults.
  • A1C is a size that indicates your common blood sugar degrees during the last 2 to three months. The ADA recommends an A1C intention of much less than 7% for maximum adults.

Farxiga Familiar

Farxiga is the simplest to be had as a brand-call drug. It consists of the drug dapagliflozin, which isn’t presently to be had in familiar form.

Farxiga Facet Outcomes

Farxiga can purpose moderate or severe facet outcomes. The following listing consists of a number of the important thing facet outcomes that could arise whilst taking Farxiga. This listing doesn’t encompass all viable facet outcomes.


For extra facts at the viable facet outcomes of Farxiga, or suggestions on a way to address a troubling facet impact, communicate together along with your health practitioner or pharmacist.

Note: The Food and Drug Administration (FDA) tracks facet outcomes of medicine it has approved. If you would love to file to the FDA a facet impact you’ve had with Farxiga, you may accomplish that via MedWatch.

More Not Unusual Place Facet Outcomes

The extra not unusual place facet outcomes of Farxiga can encompass:

  • vaginal yeast contamination
  • respiration infections, inclusive of the not unusual place bloodless or the flu
  • urinary tract contamination
  • multiplied urination
  • genital contamination in guys
  • again ache
  • nausea
  • multiplied ldl cholesterol tiers

Some of those facet outcomes may fit away inside some days or multiple weeks. If they’re excessive or don’t depart, communicate with your health practitioner or pharmacist.

  • This is a partial listing of moderate facet outcomes from Farxiga. To find out about different moderate facet outcomes, communicate together along with your health practitioner or pharmacist, or go to Farxiga’s remedy guide.

Serious Facet Outcomes

Serious facet outcomes from Farxiga aren’t unusual places, however, they could arise. Call your health practitioner proper away when you have severe facet outcomes. Call 911 in case your signs and symptoms experience existence-threatening or in case you assume you’re having a scientific emergency.

Serious facet outcomes and their signs and symptoms can encompass the following:

  • Dehydration (low fluid level) and occasional blood pressure. Symptoms can encompass:
  • weak point, particularly while you stand up
  • Low blood sugar level (hypoglycemia). Symptoms can encompass:
  • Drowsiness
  • Dizziness
  • Feeling faint
  • Lightheadedness
  • Headache
  • Weak point
  • Hunger
  • Confusion
  • Irritability
  • Severe allergy.
  • Kidney harm.
  • Serious urinary tract infections (utis).
  • Sweating
  • Feeling jittery
  • Speedy heartbeat
  • Fournier’s gangrene (necrotizing fasciitis of the perineum).

For facts approximately those severe facet outcomes of Farxiga, see the “Side impact details” phase simply below.

Side Impact Details

You might also additionally marvel at how regularly positive facet outcomes arise with this drug, or whether or not positive facet outcomes pertain to it.Here’s a few elements on numerous of the facet outcomes this drug might also additionally or won’t purpose.

Allergic Reaction

As with maximum capsules, a few humans may have an allergy after taking Farxiga. In scientific research, 0.three% of folks who took Farxiga had an allergy to it.

Symptoms of a moderate allergy can encompass:

  • Pores and skin rash
  • Itchiness
  • Flushing (warm temperature and redness to your pores and skin)

An extra excessive allergy is uncommon however viable. Symptoms of an excessive allergy can encompass:

  • swelling beneathneath your pores and skin, generally to your eyelids, lips, hands, or feet
  • swelling of your tongue, mouth, or throat
  • hassle breathing

Call your health practitioner proper away when you have an excessive allergy to Farxiga. But name 911 in case your signs and symptoms experience existence-threatening or in case you assume you’re having a scientific emergency.

Weight Loss

A useful facet impact of Farxiga is weight loss. In scientific research, humans taking Farxiga misplaced as much as approximately 7 pounds (three kilograms) over 24 weeks of remedy.

Farxiga have to simplest be used in step with your health practitioner’s prescription. You shouldn’t use Farxiga with out your health practitioner’s guidance.

Bladder Most Cancers

There can be a connection among Farxiga and bladder most cancers, however, it’s now no longer positive.

In scientific studiesTrusted Source, extra humans taking Farxiga had bladder most cancers in comparison to humans taking a placebo.

In 22 research, 6,1/2 humans took Farxiga and 10 had bladder most cancers. In the three,512 folks who took a placebo or an evaluation drug, one individual had bladder most cancers. (A placebo is a remedy without a lively drug.)

However, in step with the Food and Drug Administration (FDA), there isn’t sufficient facts to understand if Farxiga changed into the purpose of bladder most cancers in those cases.

Back Ache

In scientific research, again ache came about in as much as 4% of humans taking Farxiga. This facet impact may fit away with endured use of the drug. If you’ve got again ache that doesn’t depart or will become excessive, communicate together along with your health practitioner.

Kidney Harm

Farxiga can growth your danger of kidney harm. Symptoms of kidney harm can encompass:

  • Decreased Urination
  • Swelling To Your Legs Or Ankles
  • Confusion

This facet impact didn’t arise in scientific assessments of Farxiga, however, later reviews have referred to it.

Kidney troubles are much more likely to arise in case you’re dehydrated, have kidney or coronary heart troubles, or are over the age of sixty-five years. They’re additionally much more likely in case you take different medicines that have an effect on your kidneys.

Before you begin taking Farxiga, your health practitioner will take a look at how properly your kidneys are working. If you’ve got kidney troubles, you can now no longer be capable of taking Farxiga.

Your health practitioner might also take a look at your kidney feature occasionally for the duration of your remedy with Farxiga. If they locate any troubles together along with your kidneys, they will prevent your remedy with the drug.

Yeast Contamination

Farxiga can growth your danger of genital yeast contamination. In scientific research, yeast contamination came about in as much as approximately 8% of ladies and approximately three% of guys taking Farxiga.

Genital yeast contamination in guys can purpose a rash or redness at the penis. This situation is referred to as balanitis or balanoposthitis, relying on what a part of the penis is affected.

If you are taking Farxiga and get a rash or redness to your genitals, communicate together along with your health practitioner. They might also additionally prescribe a remedy to deal with the contamination.

Urinary Tract Contamination (UTI)

Farxiga can grow your danger of urinary tract contamination (UTI). In scientific research, UTI came about in as much as approximately 6% of humans taking the drug.

Symptoms of UTI can encompass:

  • burning sensation while urinating
  • the want to urinate extra regularly
  • the want to urinate proper away
  • ache withinside the decrease a part of your abdomen (belly)
  • blood to your urine

If you watched you would possibly have a UTI, name your health practitioner. They can test to look when you have a UTI, and they’ll suggest remedy if needed.

Ketoacidosis

Although uncommon, a few folks who take Farxiga can expand a severe situation referred to as diabetic ketoacidosis.

This situation happens while the cells of your frame aren’t getting the glucose they want for energy. Instead, your frame makes use of fats for energy, that can purpose excessive tiers of chemical substances to your blood referred to as ketones. Also, your blood can emerge as too acidic. In excessive cases, this situation can purpose coma or death.

The first signs and symptoms of ketoacidosis generally encompass:

  • Thirst and dry mouth
  • Urinating extra regularly than usual
  • Excessive blood sugar tiers
  • Excessive tiers of ketones to your urine

Later signs and symptoms might also additionally encompass:

  • Nausea and vomiting
  • Ache to your abdomen (belly)
  • Weak point or fatigue (loss of energy)
  • Fruity-smelling breath
  • Hassle breathing
  • Confusion

If you’ve got any of those signs and symptoms, name your health practitioner proper away. If your signs and symptoms are excessive, name 911 or visit the closest emergency room.

Fournier’s Gangrene

While it hasn’t came about in scientific research of Farxiga, a situation referred to as Fournier’s gangrene has been said in humans the usage of Farxiga and different capsules in its class.

Also referred to as necrotizing fasciitis of the perineum, it’s an contamination of the location among the genitals and the rectum. This situation is uncommon however may be existence threatening, and it is able to have an effect on each guys and ladies.

Symptoms of Fournier’s gangrene can encompass:

  • Ache, tenderness, swelling, or reddening withinside the genital or rectal location
  • Fever
  • Malaise (usual feeling of discomfort)

Fournier’s gangrene calls for instantaneous care, that could encompass remedy, hospitalization, or surgery. If you’re taking Farxiga and feature signs and symptoms of this situation, name your health practitioner proper away.

Farxiga Dosage

Typically, your health practitioner will begin you on a low dosage of Farxiga and can growth it to attain the dosage that’s proper for you. Their intention could be the smallest dosage that offers the preferred effect.

The following statistics describe dosages that can be normally used or recommended. However, make sure to take the dosage your health practitioner prescribes for you. Your health practitioner will decide the first-rate dosage to fit your needs.

Drug Paperwork And Strengths

Farxiga comes as a pill you are taking with the aid of using mouth. It’s to be had in  strengths: five milligrams (mg) and 10 mg.

Dosage For Kind 2 Diabetes

The regular beginning dosage of Farxiga for kind 2 diabetes is five mg as soon as daily. This dose is taken withinside the morning.

If this dosage of Farxiga doesn’t decrease your blood sugar ranges enough (and it additionally doesn’t motive troubling aspect effects), your health practitioner might also additionally growth your dosage to ten mg as soon as daily.

The most dosage of Farxiga for kind 2 diabetes is 10 mg as soon as daily.

The dosage to lessen the threat of hospitalization for coronary heart failure in humans with kind 2 diabetes and coronary heart sickness or threat elements for coronary heart sickness is 10 mg as soon as daily.

Dosage For Coronary Heart Failure

Farxiga is authorized to decrease the threat of positive headaches of coronary heart failure in adults who don’t have kind 2 diabetes. (For extra statistics approximately this, see the segment underneath called “Farxiga uses.”) The regular dosage for this use is 10 mg as soon as daily.

What If I Pass Over A Dose?

If you pass over a dose, take it as quickly as you remember. If it’s nearly time in your subsequent dose, simply take that one dose. Don’t try and trap up with the aid of using taking  doses at as soon as. This can motive risky aspect effects.

Will I Want To Apply This Drug Lengthy Time Period?

Farxiga is supposed for use as a lengthy-time period treatment. If you and your health practitioner decide that Farxiga is secure and powerful for you, you’ll in all likelihood take it lengthy time period.

Do I Want To Take This Drug With Food?

Farxiga may be interested in or with out food.

Makes Use Of Farxiga

The Food and Drug Administration (FDA) approves prescribed drugs which includes Farxiga to deal with sure situations. Farxiga will also be used off-label for different situations. Off-label use is while a drug that’s accepted to deal with one situation is used to deal with an exceptional situation.

Below, we describe Farxiga’s accepted makes use of. But it’s crucial to be aware that Farxiga isn’t accepted to deal with kind 1 diabetes. And the drug additionally shouldn’t be used to deal with diabetic ketoacidosis (DKA), that’s a lifestyles threatening situation that’s associated with diabetes.

Farxiga For Kind 2 Diabetes

Farxiga is FDA-accepted to be used in adults with kind 2 diabetes to:

  • Enhance blood sugar stages while used in conjunction with progressed weight loss program and exercise
  • Lessen the chance of hospitalization for coronary heart failure in human beings with both coronary heart sickness or chance elements* for coronary heart sickness

Diabetes is a chronic (long-lasting) situation. With diabetes, the extent of sugar (glucose) to your bloodstream builds up. Normally, a hormone known as insulin allows to transport glucose out of your bloodstream into your cells. (Once interior your cells, glucose is used to make energy.)

But with kind 2 diabetes, your frame’s cells don’t reply to insulin in addition to they must. And withinside the later degrees of diabetes, your frame additionally won’t make sufficient insulin.

Having kind 2 diabetes that’s now no longer controlled can purpose your blood glucose stage to be excessive all of the time. And this could purpose numerous signs which can result in critical complications, which includes coronary heart failure.

  • Some examples of chance elements for coronary heart sickness consist of being of an older age, having excessive ldl cholesterol or excessive blood pressure, and smoking.

How Kind 2 Diabetes And Coronary Heart Failure Are Connected

Many of the chance elements and modifications in physical features are identical for each kind of 2 diabetes and coronary heart failure. So each of those situations may be a chance element for the alternative.

For example, having an excessive amount of sugar and insulin in your bloodstream additionally reasons fatty buildup and infection to your blood vessels. This weakens your coronary heart and may result in coronary heart failure. On the alternative hand, having coronary heart failure is connected to metabolic troubles (troubles together along with your frame’s cappotential to technique energy). And this could result in out-of-control blood sugar and diabetes.

In medical research, human beings with kind 2 diabetes had been to 4 instances much more likely to expand coronary heart failure. They additionally had a 50% better chance of hospitalization than a person with out diabetes.

If you’ve got coronary heart failure without diabetes, you’ve got as much as a 60% chance of growing insulin resistance. (With insulin resistance, your frame’s insulin isn’t operating because it must to transport glucose out of your bloodstream into your cells.)

Because of the hyperlink among kind 2 diabetes and coronary heart failure, capsules like Farxiga can assist enhance each situations.

Effectiveness For Glucose Manage In Kind 2 Diabetes

A big quantity of medical trials were achieved on Farxiga in human beings with kind 2 diabetes. In a few research, exceptional doses of Farxiga on my own had been in comparison with a placebo (remedy and not using a lively drug).

In a different research, mixtures of Farxiga and different diabetes capsules had been in comparison with a placebo or exceptional diabetes drug. These different diabetes capsules consist of metformin, glipizide, glimepiride, glyburide, pioglitazone, sitagliptin, exenatide, and insulin.

One medical have a look at in comparison remedy with Farxiga on my own to that of a placebo in human beings with newly recognized kind 2 diabetes. After 24 weeks of remedy:

  • Human beings taking Farxiga five mg had their fasting blood sugar* stages reduced through 24.1 mg/dl and their hemoglobin A1c (A1C)† stage changed into decreased through 0.eight%.
  • Human beings taking Farxiga 10 mg had their fasting blood sugar stages reduced through 28.8 mg/dl and their A1C stage decreased through 0.9%.
  • Human beings taking the placebo had their fasting blood sugar stages reduced through four.1 mg/dl and their A1C stage decreased through 0.2%.

About 44% to 51% of human beings on this have a look at who took Farxiga for twenty-four weeks reached their aim A1C of much less than 7%. In the placebo group, simplest approximately 32% of human beings reached their aim.

Other medical research checked out remedies with Farxiga in aggregate with different diabetes capsules in human beings with kind 2 diabetes. The research confirmed that the human beings had comparable or higher consequences as human beings taking Farxiga on my own.

  • Fasting blood sugar is measured after you’ve fasted for a sure length of time. The American Diabetes Association (ADA) recommends a fasting blood sugar stage of eighty mg/dL to a hundred thirty mg/dL for maximum adults.
  • A1C is a size that suggests your common blood sugar stages during the last 2 to a few months. The ADA recommends an A1C aim of much less than 7% for maximum adults.

Effectiveness For Lowering Hospitalization Chance From Coronary Heart Failure In Kind 2 Diabetes

In a medical have a look at, human beings taking Farxiga had a 27% decrease charge of hospitalization because of coronary heart failure than did human beings taking a placebo. (A placebo is a remedy and not using a lively drug.) People on this have a look at had kind 2 diabetes. And they had been accompanied for approximately four years.

Farxiga For Coronary Heart Failure

Farxiga is accepted to be used in adults with coronary heart failure who don’t have kind 2 diabetes. For this use, the drug is given to human beings with decreased ejection fraction (EF)* to lessen the chance of both:

  • hospitalization for coronary heart failure, or
  • dying that’s associated with a coronary heart or blood vessel problem [LP2]
  • With decreased EF, your coronary heart isn’t capable of pump out as an awful lot blood to the relaxation of your frame as usual.

With coronary heart failure, your coronary heart isn’t operating as properly to pump blood in the course of your frame. Without sufficient blood flow, your frame can’t characteristic normally. Typical signs of coronary heart failure can consist of:

  • Shortness of breath
  • Tiredness
  • Edema (swelling) to your legs, ankles, and feet

Effectiveness For Lowering Dying In Coronary Heart Failure

In a medical have a look at, human beings taking Farxiga had an 18% decrease in charge of dying because of coronary heart or blood vessel troubles in comparison with human beings taking a placebo. (A placebo is a remedy and not using a lively drug). People on this have a look at had been accompanied for 18 months.

Effectiveness For Lowering Hospitalization Chance Of Coronary Heart Failure

In the identical medical have a look at as above, human beings taking Farxiga had a 30% decrease chance of being hospitalized for coronary heart failure in comparison with human beings taking a placebo.

Other Viable Makes Use Of For Farxiga

The FDA hasn’t accepted different makes use of Farxiga. However, the drug can be used off-label for sure purposes. Off-label use is while a drug is accepted for one reason however is prescribed for an exceptional reason.

Farxiga For Kind 1 Diabetes

Farxiga is accepted to deal with kind 2 diabetes. But it’s now no longer acceptable to deal with kind 1 diabetes. In one medical studyTrusted Source, Farxiga decreased blood sugar stages, hemoglobin A1c (HbA1c),* and general day-by-day insulin doses in human beings with kind 1 diabetes. However, proper now there’s now no longer sufficient records to be had at the protection and effectiveness of the use of Farxiga in human beings with kind 1 diabetes. So using Farxiga for kind 1 diabetes isn’t recommended.

  • A1C is a size that suggests your common blood sugar stages during the last 2 to a few months. The American Diabetes Association (ADA) recommends an A1C aim of much less than 7% for maximum adults.

Farxiga For Weight Loss

Many human beings with diabetes who take Farxiga lose weight, that’s a useful aspect effect. Your physician might also additionally suggest Farxiga for you when you have kind 2 diabetes and also are overweight.

But preserve in thoughts that Farxiga hasn’t been studied or accepted as a resource to weight loss. You must simplest take Farxiga as prescribed through your physician.

While Farxiga isn’t accredited as a weightloss medication, weight reduction is a useful facet impact of the drug.

In scientific studies, humans taking Farxiga misplaced as much as approximately 7 pounds (three kilograms) over 24 weeks of treatment. Because of this facet impact, your medical doctor might also additionally propose Farxiga when you have kind 2 diabetes and also are overweight.

It’s idea that Farxiga reasons weight reduction as it sends more glucose (sugar) out of your blood into your urine. That way the energy from the glucose depart your frame for your urine, which might also additionally result in weight reduction.

Note: Farxiga must most effectively be used in line with your medical doctor’s prescription. You shouldn’t use Farxiga for weight reduction or every other reason without your medical doctor’s guidance.

Farxiga Price

As with all medications, the value of Farxiga can vary. To discover present-day expenses for Farxiga in your area, take a look at our Amazon.com.

The value you discover on Amazon.com is what you could pay without coverage. The real rate you’ll pay relies upon for your coverage plan, your location, and the drugstore you use.

Your coverage plan may also require you to get previous authorization earlier than approving insurance for Farxiga. This way that your medical doctor and coverage business enterprise will want to speak approximately your prescription earlier than the coverage business enterprise will cowl the drug. The coverage business enterprise will evaluation the previous authorization request and determine if the drug can be covered.

If you’re now no longer certain if you’ll want to get previous authorization for Farxiga, touch your coverage business enterprise.

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